Outcome in critically ill patients with candidal fungaemia: Candida albicans vs. Candida glabrata

Blot, S.;Vandewoude, K.;Hoste, E.;Poelaert, J.;Colardyn, F.

Author address: 

Blot, S, State Univ Ghent Hosp, Dept Intens Care, De Pintelaan 185, B-9000 Ghent, Belgium


In a retrospective study (1 January 1992-12 December 1998), we investigated population characteristics and outcome in critically ill patients with fungaemia involving C. albicans (n=41) and C. glabrata (n=15). Patients with C. glabrata fungaemia were significantly older compared with patients in the C. albicans group (P=0.024). There were no other differences in population characteristics or severity of illness. Logistic regression analysis showed age (P=0.021), the presence of a polymicrobial blood stream infection (P=0.039), and renal failure (P=0.044) to be independent predictors of mortality. There was no significant difference in in-hospital mortality between the C. glabrata and C. albicans groups (60.0% vs. 41.5%; P=0.24). Since age was an independent predictor of mortality, the trend towards a higher mortality in patients with C. glabrata can be explained by this population being significantly older. In conclusion, ne found no difference in mortality between patients with fungaemia involving C. albicans and C. glabrata. (C) 2001 The Hospital Infection Society.

abstract No: 


Full conference title: 

39th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
    • ICAAC 39th