A novel motif in fungal Class 1 Histone deacetylases is essential for growth and development of Aspergillus

Ingo Bauer, Martin Tribus, Johannes Galehr, Birgit Faber, Divyavaradhi Varadarajan, Gerald Brosch, Stefan Graessl

Abstract: 

ct class=mceAdvanced>In eukaryotic organisms DNA is compacted into an elaborate structure called chromatin, thus enabling regulation of transcription by controlling the accessibility of the genetic information for transcription factors. Among the key players involved in the regulation of chromatin structure are histone acetyltransferases and histone deacetylases (HDACs) —enzymes establishing distinct acetylation patterns in the N- terminal tails of core histones. In filamentous fungi only little is known about the biological functions of these enzymes
2010

Full conference title: 

10th EUROPEAN CONFERENCE ON FUNGAL GENETICS
    • ECFG 10th (2010)