Nidulin

Toxin: 

n

Trivial name: 

11H-​Dibenzo[b,​e]​[1,​4]​dioxepin-​11-​one, 2,​4,​7-​trichloro-​3-​hydroxy-​8-​methoxy-​1,​9-​dimethyl-​6-​(1-​methyl-​1-​propenyl)​-​, (E)​-; 11H-​Dibenzo[b,​e]​[1,​4]​dioxepin-​11-​one, 2,​4,​7-​trichloro-​3-​hydroxy-​8-​methoxy-​1,​9-​dimethyl-​6-​(1-​methylpropenyl)​- (8CI); 11H-​Dibenzo[b,​e]​[1,​4]​dioxepin-​11-​one, 2,​4,​7-​trichloro-​3-​hydroxy-​8-​methoxy-​1,​9-​dimethyl-​6-​[(1E)​-​1-​methyl-​1-​propenyl]​- (9CI); Nidulin (6CI,​7CI); 4,​2-​Cresotic acid, 3,​5-​dichloro-​6-​[5-​chloro-​2-​hydroxy-​4-​methoxy-​6-​(1-​methylpropenyl)​-​m-​tolyloxy]​-​, ε-​lactone

Systematic name: 

11H-​Dibenzo[b,​e]​[1,​4]​dioxepin-​11-​one, 2,​4,​7-​trichloro-​3-​hydroxy-​8-​methoxy-​1,​9-​dimethyl-​6-​[(1E)​-​1-​methyl-​1-​propen-​1-​yl]​-

Molecular formulae: 

C20H17Cl3O5

Molecular weight: 

443.70

Chem abstract number: 

10089-10-8

Literature reference: 

Nidulin and ustin-​two chlorine-​containing metabolic products of Aspergillus nidulans. Dean, F. M.; Robertson, A.; Roberts, John C.; Raper, K. B. Nature (London, United Kingdom) (1953), 172, 344. Studies on fungal products. XVIII. Isolation and structures of a new fungal depsidone related to nidulin and a new phthalide from Emericella unguis. Kawahara, Nobuo; Nakajima, Shoichi; Satoh, Yumiko; Yamazaki, Mikio; Kawai, Kenichi. Chemical & Pharmaceutical Bulletin (1988), 36(6), 1970-5.

Structure image: 

Aspergillus Species known to produce this metabolite: 

3d image file .c3d (requires Chem3d http://www.cambridgesoft.com/Ensemble_for_Chemistry/ChemBio3D/): 

jmol file (.mol) requires Java to run (http://www.java.com/en/download/help/enable_panel.xml): 


Date uploaded: 

2008-07-07 16:58:01