Microsphaeropsis spp. belong to the Coelomycete class of fungi and are plant pathogens. Microsphaeropsis olivacea has been reported as the causative agent in one case of skin infection and in one case of fungal keratitis. We report three cases of skin infection with a plant pathogen, Microsphaeropsis arundinis. To our knowledge, this has not been described previously as a cause of infection in mammals. The first isolate was obtained from a patient with myelofibrosis on prednisolone therapy. A tissue sample from a granulomatous plaque on the dorsum of the hand yielded the fungus. The second isolate was obtained from a diabetic patient with renal disease. The fungus was isolated from ulcerating lesions on the leg at three separate sites. The third isolate was obtained from the forelimb of a cat. The immune status of the cat was unknown. All three samples were positive on histopathological examination and direct microscopy for fungal elements. All were identified to species level on culture. The outcome for all three cases was satisfactory. Two cases were cured by amputation (cat and diabetic patient) whilst the third resolved with antifungal therapy.
Full conference title:
The 15 th Congress of the International Society for Human and Animal Mycology
- ISHAM 15th (2003)