Objectives: Clinical, epidemiological and therapeutical study about 4 cases of leishmaniasis in travellers in endemic areas. Methods: Retrospective study about 4 patients with leishmaniasis hospitalized in Clinical Infectious Diseases Hospital of Constaní¾a, Romania, during 2005. Diagnosis was histologically and microbiologically confirmed. Treatment consisted of: sodium stibogluconate in one case, meglumine antimonate in 2 cases, and amphotericin B in one case. Clinical follow-up was conducted daily during treatment and 2 months afterwards. Results: Diagnosis: cutaneous leishmaniasis in 3 patients (2 males and one female) and visceral leismaniasis in one patient (female); age of the patients: between 30 and 55 years old. All travelled in endemic areas. Examination showed nodular lesions and depressed central ulceration all over the body. All lesions and the clinical manifestations (for visceral leishmaniasis) were improved at the end of therapy. For the patient treated with amphotericin B, some brown spots appeared on the hands and soles, on the end of therapy, like adverse event, but disappeared after one week. Conclusions: Romania is not an endemic area for leishmaniasis, but in the last years cases were related because of the person's circulation in touristic, professional and humanitarian purposes.
Full conference title:
16th European Congress of Clinical Microbiology and Infectious Diseases
- ECCMID 16th (2006)