Laboratory outcomes for (1,3) beta D-glucan detection in adult neutropenic patients with haematological malignancies

Velegraki, A., Velegraki, A., Yiakoumis, X., Alexopoulos, E.C., Andreopoulos, A., Milioni2, A., Kritikou1, S., Ilia1, I., Aggelopoulou3, M., Dimitriadou3, E., Vaiopoulos3, G., Pangalis3, G.A.

Author address: 

1 Medical School, University of Athens, ATHENS, Greece 2Mycology Laboratory, Department of Microbiology, ATHENS, Greece 31st Department Internal Med., Laikon Medical School, UNIVERSITY OF ATHENS, Greece 4Hygiene, Medical School, University of

Abstract: 

The recent introduction of the beta glucan test in serum for the detection and quantification of circulating fungal (1,3) beta D-glucan, a major cell wall constituent of various medically important fungi, can assist in the presumptive diagnosis of invasive fungal infection in high-risk groups of patients. From January 2007 to April 2007 we assessed the performance of the test in 14 high-risk neutropenic (polymorphonuclear leucocyte count 100 pg/ml in the 10 patients with proven and possible aspergillosis, whereas cultures were negative in all 8 patients with possible aspergillosis. Agreement of PCR versus GM detection test was 0.771 (p
2007

abstract No: 

P152

Full conference title: 

3rd Trends in Medical Mycology
    • TIMM 3rd (2011)