RATIONALE: Health care costs have been increasing in emergency visits for asthmatic children. Various factors have been associated with high risk of emergency visits and vary amongst populations. Identification of risk factors will help to improve asthma management and health care outcomes in children. METHODS: Common indoor allergens such as cat, dog, rodent, dust mite, roach, alternaria, aspergillus, cladosporium, and penicillium levels were tested in dust samples collected from the house of asthmatic children in a healthy home project. The health status such as allergic sensitization, asthma severity and emergency visits for asthma and related information were collected, and examined in an association with environmental exposure. RESULTS: Higher dust cat and dog allergens were significantly associated with a lower rate of at least once emergency visit in the past 12 months (p=0.009 for cat allergen and p=0.013 for dog allergen) in asthmatic patients. Similar trends were observed for dust mite, cockroach, alternaria, aspergillus, cladosporium, and penicillium rather than rodent allergen although no significance was found. No significance was observed in association with age, gender and ethnicity/race. CONCLUSIONS: A lower level of cat and dog allergens in the environment may not always be associated with lower risk of emergency visits in asthmatic patients. The mechanism behind these observations remains to be further illustrated.
Full conference title:
American Academy of Allergy Asthma & Immunology
- AAAAI 2011 (67th)