Hypersensitivity Testing for Aspergillus fumigatus Immunoglobulin E (IgE) is Significantly More Sensitive Than Testing for Aspergillus niger IgE

T.A. Selvaggi1, J.P. Walco2, R. Sharma3

Author address: 

1 Hackensack University Medical Center, Hackensack, NJ 2 Cornell University, Ithaca, NY 3 University of Medicine and Dentistry - New Jersey Medical School, Newark, NJ


Rationale We noted that some clinicians order specific IgE testing for both Aspergillus fumigatus (A fumigatus) and Aspergillus niger (A niger) to detect Aspergillus hypersensitivity. We sought to determine if the elimination one of the assays would be clinically relevant. Methods We reviewed 5 years of allergy testing at a regional laboratory in Northern New Jersey comparing serum allergy hypersensitivity to A fumigatus with serum allergy hypersensitivity to A niger using the Pharmacia Unicap system. 109 clinical specimens were evaluated using Fisher's exact test as an index of concordance among paired results. Results There was a significant difference between 109 paired samples for the presence of serum sensitivity to A fumigatus and A niger (p

abstract No: 


Full conference title: 

2008 American Academy of Allergy, Asthma, and Immunology Annual Meeting
    • AAAAI 2008 (64th)