Genome dynamics in the Fusarium oxysporum species complex.

Martijn Rep1, Li-Jun Ma3, H. Corby Kistler3, Charlotte van der Does1,4, Ido Vlaardingerbroek1, Shermineh Shahi1, Petra Houterman1, Ben Cornelissen1 and Sarah M. Schmidt1.

Author address: 

1 Plant Pathology, Swammerdam Institute for Life Sciences, University of Amsterdam, P.O. Box 94215, 1090 GE Amsterdam, The Netherlands. 2 Broad Institute, Cambridge, MA / University of Massachusetts Amherst, MA, USA. 3 Plant Pathology, College of F


The Fusarium oxysporum species complex is a collection of apparently asexually propagating clonal lines. The complex is well known for its genetic diversity, ecological versatility including host-specific pathogenicity, karyotope variability and transposon richness. It is now clear that these phenomena are correlated to the presence of lineage-specific (LS) genomic regions of many megabases as an addition to a conserved ’core’ genome. These regions are present as either entire LS chromosomes or extensions to core chromosomes and can constitute as much as 25% of the entire genome. The LS genomic regions contain the bulk of the transposons, are extremely variable in organisation even within a clonal line and highly diverse in gene composition between clonal lines. Some LS chromosomes contain genes involved in virulence towards plants and can be transferred horizontally between clonal lines. Through comparative genomics of strains from different clonal lines and with different host-specificity we aim to better understand the evolutionary dynamics of the LS metagenome of the Fusarium oxysporum species complex.

abstract No: 


Full conference title: 

26th Fungal Genetics Conference
    • Fungal Genetics Conference 26th (2005)