Fungal resistance

Bernhardt, H.;Zimmermann, K.;Knoke, M.

Author address: 

Bernhardt, H, Univ Greifswald, Klin Innere Med A, Loefflerstr 23 A, D-17489 Greifswald, Germany


Fungal resistance is caused by an acquisition of intrinsically resistant species, by selection of resistant strains from a population or by mutation of an initially susceptible strain. According to different classes of antimycotics there are different resistance mechanisms: differences in the uptake mechanisms, drug target alterations, mostly the ergosterol- biosynthesis pathway and the efflux or pumping mechanisms to the outside.

abstract No: 


Full conference title: 

International Satellite Symposium to the 9th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
    • ECCMID 9th (1999)