Fungal infections (FI) in cystic fibrosis (CF)

Castagnola1, E., Gaslini2, G.


FI are not frequent complications in patients with CF, and are represented by 3 main conditions. Allergic bronchopulmonary aspergillosis (ABPA): is characterized by chronic airway inflammation and airway damage resulting from persistent colonization by and sensitization to Aspergillus fumigatus, which leads to worsening airway inflammation and progressive damage to the lungs. ABPA is diagnosed by specific criteria: (1) asthma; (2) chest roentgenographic infiltrates (not essential for diagnosis); (3) immediate cutaneous reactivity to Aspergillus species; (4) total serum IgE > 1000 ng/mL (greater than 500 IU/mL as the minimal diagnostic criterion.)

Full conference title: 

3rd Trends in Medical Mycology
    • TIMM 3rd (2011)