Fifteen patients suffering from polyposis (n=13 ), fungus ball (n=1), and inverted papillioma (n=I), were examinated for presence of fungal agent in nasosinusal secretion and mucus. For each patient bilateral nasal Iavage were carried out and specimens (polyposis, fungus ball) were obtained for culture ; in both cases under surgically sterile conditions. Presence of specific Aspergillus IgE and galactomannan antigen was searched on nasal secretions and specimens. Results: Most of (lavages and specimens remained negative for mycology (direct, culture and antigens). Except in fungal balls cases, fungal agents are rare. In return, specific IgE were found for isolated case of polyposis. We conclude that actually, fungal agent may not be considered as pathologic agent in the pathophysiology of nasal polyposis. Nevetherless further studies are necessary to confirm these preliminary results.
Full conference title:
Focus on Fungal Infections 11, March 14-16 2001
- Focus on Fungal Infection 11 (2001)