Objective: Infection remains the major problem of the burn patients. Most common infectious complication involving the burn wound. Fungal burn infections occurs most often in patients with extensive burn wound injury, that recently emerged as a distinct clinicopathological entity, responsible for both mortality and morbidity. Materials and methods: During a 2 year September 2002 to September 2004, of patients with thermal injury admitted to hospital burn, Swab specimens were obtained from areas of the burn wound suspected to be harbouring infection. Diagnosis of fungal burn wound confirmed by microscopic examination and culture of the specimens on SDA medium with antibiotic chloramphenicol. Fungi Sp. was cultured at any time during their hospital cause were selected for study. Results: 25% (250 case) of these patients had colonization with fungi species one or more site during acutely hospitalized study, although 10% of these patients had positive microscopy examination. Patients with fungal burn wound infections had age amean of 28 years and a mean burn size of 63% of the total body surface area. A mean burn day was 10 day. Majority to have third degree burn (75%) and majority of this patients were male (70%). 2% (5 case) of the patients with fungal burn wound infection died disseminated fungal disease. All of the patients had culture positive been receiving broad spectrum antibiotics with an average of 15 days. 40% (100 case) Candidia Sp, 30% ( case) Aspergillus Sp. and 20% (50 case) Zygomycet Sp. were organisms fungi most frequently responsible for clinical mycotic burn wound infections. Candida albicans was predominant species isolated, remained Aspergillus fumigatus, Candida tropicalis, Phycomyces Sp., Fusarium Sp., Acromonium Sp., Malassezia Sp., Penicillum Sp., Geotrichum Sp. were aetiological agent fungal burn wound infections. Conclusion: In burn patients lose of the normal flora of the body impairment of immunity system, contribute to the increased susceptibility to fungal burn wound infection. Among the fungi candida albicans which is an opportunistic microorganism and one the normal flora to create more difficult burn patients. In conclusion although fungal infections remained a significant source of morbidity, it was associated with a low rate of mortality, large areas of open wound and exposure borad-spectrum antibiotic were associated with the development of fungal burn wound infections.
Full conference title:
- ECCMID 15th (2005)