Expression of recombinant fungal proteins with potential relationship to fungal allergy.

Torrecilla, Ignacio1; Lawrence, Christopher B2; Dunn-Coleman, Nigel S1; and Dí­az-Torres, Marí­a R.

Author address: 

1AlerGenetica SL, Santa Cruz de Tenerife, Spain.


Allergies are the fourth most common disease in the world with between 40-50% of the World’s population affected. A substantial portion of this population (10-30%) is allergic to filamentous fungi present in the environment with patients suffering from allergic rhinitis to more severe cases of asthma. At present there is no curative treatment for fungal allergy. AlerGenetica, in collaboration with the Universities of Barcelona and Manchester, intends to profile which fungal allergens patients are sensitized to. The initial focus of the research is profiling patients sensitized to allergens from Aspergillus fumigatus and Alternaria alternata. In order to express these allergens, we have selected two expression systems: Pichia pastoris, and Aspergillus niger. This research is partially funded by the Torres Quevedo Program of the Spanish Science and Innovation Department.

abstract No: 


Full conference title: 

26th Fungal Genetics Conference
    • Fungal Genetics Conference 26th (2005)