The decision to treat patients with primary coccidioidomycosis sis (CM) is fraught with uncertainty. An ongoing epidemic in Kern County California provided opportunity to evaluate treatment in a community based retrospective analysis. Forty eight percent of patients received drug treatment. Response analysis of treated cases revealed a worse outcome compared to nontreated cases. To evaluate a treatment effect in a comparable population, the following patients were excluded: those cases with early death, given amphotericin B in 1:32, dissemination, and chronic disease. Combined serious disease endpoints were reduced by 68 percent.
Full conference title:
Coccidioidomycosis - Centennial Conference