Personal investigations, which have been carried out for 4 years, proved that the magnetic field inhibits the growth of some pathogenic dermatophytes cultured in vitro. The aim of this study was comparision of the effects of magnetic field and terbinafine on laboratory animals infected by dermatophytes. The experiments were carried out on guinea pigs, which were 2 month old, males and kept in standard conditions. The animal was infected in scarificated skin of the back. (the density of the suspension was 9 x 108 spores investigated fungal species per ml). Then it was left alone till the appearance of fungal lesion on the skin, whose diameter would be at least 1 cm. In the study species: T. mentagrophytes and M. canis were chosen. Infected animals were selected to one of the three research groups : 1/ group treated with terbinafine used superficially and to intestinal tract, 2/ group treated by magnetic field, and 3/ control group. Apparatus Magnetronic MF-10 was used to magnetic stimulation. It generated changeable magnetic field ELF (frequency of 50 Hz, daily stimulating time up to 12 hours). The period of investigation was the time from the start of the infection to healing of the animal (2-3 months). In order to estimate the effectiveness of therapy, the method of computer planimetry was applied. The area changed by illness was measured by digital camera (once a week) and it was analyzed by means of software package MultiScanBase v 8.08. We observed the inhibiting effect of magnetic field on the development of the skin lesions of some infected animals.
Full conference title:
6th Congress of the European Confederation of Medical Mycology Societies
- ECMM 6th (2000)