Differences in Allergen Exposures Between American Asthmatic and Nonasthmatic Homes

Jianfeng J.M. Meng, Charles Barnes, Lanny Rosenwasser

Abstract: 

Rationale

Asthmatic visits for allergic asthmatic patients are increased seasonally. Our previous studies indicated that certain fungal species in air sampling are significantly different between asthmatic and nonasthamtic homes. To explore allergens that may potentially account for increased asthmatic clinical visits, more allergens and bacterial levels were compared between asthmatic and nonasthmatic homes.

Methods

Total 90 Asthmatic homes were recruited and analyzed in high allergen seasons and 90 non asthmatic homes were recruited and analyzed mostly in low (visiting) allergen seasons. Allergen levels for alt, asp, cat, clad, dog, mite, penicillin, roach and rodent from dust collections in house composite and subject rooms were examined using Elisa assays. Bacteria levels in kitchen and bath were measured too.

Results

The average allergen levels for cat, clad, penicillin and roach from both home composites and subject rooms were significantly higher in asthmatic homes than in nonasthamtic homes while no significance for others were found. The average gram positive bacilli level from both kitchen and bath was also significantly higher in asthmatic homes than that in non asthmatic homes.

Conclusions

The current observation confirmed that certain fungal species exist at different level between asthmatic at high visiting seasons and nonasthmatic homes in low visiting seasons. Furthermore, cat and roach allergens, and gram positive bacilli are different too. These may potentially account for increased clinical visits for asthmatic patients and should be removed for the prevention of asthmatic exacerbation.

Journal of Allergy and Clinical Immunology, Vol. 131, Issue 2, AB162

http://dx.doi.org/10.1016/j.jaci.2012.12.1240

abstract No: 

574
    • AAAAI 2013 (69th)