Development of the Aspergillus oryzae comparative fungal genome database

Kazuhiro Iwashita, Kazutoshi Sakamoto, Osamu Yamada

Author address: 

National research institute of brewing, Japan

Abstract: 

By the recent advancement of genome sequencing technology, the numerous numbers of genome sequences have been reported in several industrial and pathogenic fungi. The comparative genomic of these fungi will supply us huge noble information for phylogenetic study, identification of specie specific genes cluster, identification of genes function and etc. Several genome database was established including Aspergillus species and published. The genome sequence of Aspergillus oryzae was also deposited and published in these databases. However, available information is not sufficient in the point of comparative genomics, especially, comparison of well studied genome, such as Saccharomyces cerevisiae, Schizosaccharomyces pombe, Neurospora crassa, and Aspergillus nidulans. Thus, we developed Aspergillus oryzae comparative fungal genome database (NRIB CFGD) in this study. First of all, we enriched the CDS information of A. oryzae genes, such as the result of motif and domain analysis, blast analysis against KOG, COG, and Swissprot, assign of EC number and expression profile of this fungi. Furthermore, we compared the A. oryzae genome against 13 other fungal genomes. Among them, authologous genes were clustered by bidirectional best-hit analysis. These information were supplied with graphical interface and user can browse locus, transcripts, CDS, expression profiles, and result of authologous gene analysis very easily. In the comparative genome site, user can browse dot blot analysis, differential analysis and the comparison of synteny of genes. This database will be opened soon and waiting for your access.
2010

abstract No: 

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Full conference title: 

10th EUROPEAN CONFERENCE ON FUNGAL GENETICS
    • ECFG 10th (2010)