Detailed Antifungal Stewardship (AFS) is Key to Achieving Excellent Plasma Levels During Oral Posaconazole (PCZ) Prophylaxis in High Risk Hematology Patients


N. H. Hewitt, K. F. Urbancic, A. P. Grigg, M. L. Grayson
Not Known


Oral PCZ is effective antifungal prophylaxis in high risk neutropenic patients. However, achieving adequate plasma PCZ levels can be problematic due to variable absorption with the current formulation. The role of AFS and therapeutic drug monitoring (TDM) for PCZ prophylaxis remains controversial.