Deoxypodophyllotoxin

Toxin: 

n

Trivial name: 

Furo[3',​4':6,​7]​naphtho[2,​3-​d]​-​1,​3-​dioxol-​6(5aH)​-​one, 5,​8,​8a,​9-​tetrahydro-​5-​(3,​4,​5-​trimethoxyphenyl)​-​, [5R-​(5α,​5aβ,​8aα)​]​-; Podophyllotoxin, deoxy- (6CI,​7CI,​8CI); (-​)​-​Anthricin; (-​)​-​Deoxypodophyllotoxin; (-​)​-​Desoxypodophyllotoxi​n; 4-​Deoxypodophyllotoxin; AS 2-​3; Anthricin; Deoxypodophyllotoxin; Desoxypodophyllotoxi​n; Silicicolin

Systematic name: 

Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha))-

Molecular formulae: 

C22H22O7

Molecular weight: 

398.41

Chem abstract number: 

19186-35-7

Literature reference: 

Microbial transformation of an antitumor substance, deoxypodophyllotoxin. Part II. Conversion of deoxypodophyllotoxin to podophyllotoxin-​related compounds by microbes. Kondo, Kazuhiko; Ogura, Masaru; Midorikawa, Yuichiro; Kozawa, Mitsugi; Tsujibo, Hiroshi; Baba, Kimiye; Inamori, Yoshihiko. Agricultural and Biological Chemistry (1989), 53(3), 777-82. Aspergillus fumigatus Fresenius, an endophytic fungus from Juniperus communis L. Horstmann as a novel source of the anticancer pro-​drug deoxypodophyllotoxin. Kusari, S.; Lamshoeft, M.; Spiteller, M. Journal of Applied Microbiology (2009), 107...

Toxicity: 

Anticancer drug

Structure image: 

Aspergillus Species known to produce this metabolite: 

Date uploaded: 

2009-06-25 22:45:30