9H-Pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one, 10-acetyl-2,6,6a,7,11a,11b-hexahydro-11-hydroxy-7,7-dimethyl-, (6aα,11aβ,11bα)- (8CI); Cyclopiazonic acid; NSC 117181; α-Cyclopiazonic acid
9H-Pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one, 10-acetyl-2,6,6a,7,11a,11b-hexahydro-11-hydroxy-7,7-dimethyl-, (6aR,11aS,11bR)-rel-
Chem abstract number:
Production of alkaloids and related substances by fungi. XI. Isolation of cyclopiazonic imine, and bis(secodehydrocyclopiazonic acid) from the cultures of Aspergillus versicolor. Ohmomo, Sadahiro; Sugita, Masanori; Abe, Matazo. Nippon Nogei Kagaku Kaishi (1973), 47(1), 57-63. Production of cyclopiazonic acid by Aspergillus flavus Link. Luk, K. C.; Kobbe, B.; Townsend, J. M. Applied and Environmental Microbiology (1977), 33(1), 211-12. Mycotoxins of Aspergillus oryzae strains used in the food industry as starters and enzyme producing molds. Orth, R. Annales de la Nutrition et de l'...
Tremorgenic toxin. Causes degenerative changes in the liver, kidney and other organs. Intraperitoneal LD50 in the rat 2.3 mg/kg body-weight and oral LD50 of the sodium salt of cyclopiazonic acid is reported to be 19 mg/kg body-weight.
Aspergillus Species known to produce this metabolite: