Contact eczema caused by allergy to antifungal drugs is uncommon. Imidazole derivatives have been described as the most sensitising agent.
We report the case of a 49 year-old female non-atopic patient presenting with an extensive eczematous pruritic rash on her right great toe. She had been prescribed 3 weeks before a topical cream twice daily containing 0,25% amorolfine, polyethylene glicol 40 monosterate, stearyl alcohol, parafin, carbomer 934P, sodium hydroxyde, disodium edetate, 2-phenoxy ethanol and purified water. Patch test were performed with the suspected antifungal cream.
Patch test showed positive (+++) readings at 48 and 96 hours. Five control subjects obtained negative patch test with the same suspected cream. A negative result to a cosmetic battery was also included to exclude the rest of the cream components.
we describe the rare case of a contact dermatitis due to amorolfine. To our knowledge only three cases have been previously reported in the literature review.
- AAAAI 2014 (70th)