Comparison between biofilm production, phospholipase and hemolytic activity of Candida albicans and non- albicans species of Candida isolated from dental caries lesions of children

J. Udavalaxmi* and Neetha Shenoy

Author address: 

Department of Microbiology, Kasturba Medical College, LHH Road, Mangalore -575 001

Abstract: 

The study was undertaken to compare the biofilm production, phospholipase and hemolytic activity of Candida albicans and non- albicans species of Candida isolated from dental caries lesions of children. Oral swabs were collected from caries lesion of 100 school children of age 5-10 years with dental caries. Candida isolates were tested for biofilm production, phospholipase and hemolytic activity. Statistical analysis was performed using SPSS version 11.5. Out of the 100 children with dental caries 37 were positive for Candida by smear or culture. C. albicans was the most prevalent isolate followed by C. krusei, C. tropicalis and C. glabrata. Out of 21 C. albicans isolates, 9 (40.9%) of them showed phospholipase activity and 18 (85.71 %) of them produced biofilm. Of the 10 non albicans strains, 5 (50%) showed phospholipase activity and 6 (60%) produced biofilm. Even though more isolates of C. albicans produced the various virulence factors under study than the non -albicans species of Candida, the difference was not statistically relevant. ’Corresponding author E-mail:[email protected]
2014

abstract No: 

OP-029

Full conference title: 

Society for Indian Human and Animal Mycologists 2014
    • SIHAM