Colletotrichum lagenarium CST1 (Colletotrichum sterile12-like), a potential downstream transcriptional factor of a MAP kinase has homeodomain and Cys2His2 zinc finger DNA binding motifs

Yasuyuki Kubo, Gento Tsuji and Osamu Horino

Author address: 

Laboratory of Plant Pathology, Kyoto Prefectural University,Kyoto 606-8522, Japan.

Abstract: 

The infection of Colletotrichum lagenarium, the causal agent of cucumber anthracnose disease, involves several key steps: germination; formation of melanized appressoria; appressorial penetration; and subsequent invasive growth in host plants. C.lagenarium CMK1encoding a mitogen-activated protein (MAP) kinase of yeast FUS3/KSS1 homologue plays a pivotal role in these infection steps. Saccharomyces cerevisiae Ste12p is a transcriptional factor that plays a key role in coupling signal transduction through Fus3/Kss1 MAP kinase modules to specific gene expression required for mating and pseudohyphal filamentous growth. Also in pathogenic yeasts of Candida albicans and Filobasidiela neoformans, Ste12p homologues play similar roles during dimorphic transitions. In filamentous fungi, Aspergillus Ste12p homologue SteAp is required for sexual reproduction. We cloned STE12 like CST1 (Colletotrichum sterile12-like) from plant pathogenic filamentous fungi C.lagenarium encoding a protein with highly conserved homeodomain found in other Ste12 proteins. Cst1p also had C-terminal Cys2His2 zinc finger DNA binding domains retained in Ste12Ap of A. nidulans but not present in the other Ste12 proteins
2001

abstract No: 

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Full conference title: 

21st Fungal Genetics Conference
    • Fungal Genetics Conference 21st (2000)