Butyrolactone I

Toxin: 

n

Trivial name: 

Butyrolactone I
 Olomoucin

Systematic name: 

2-Furancarboxylic acid, 2,5-dihydro-4-hydroxy-2-[[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]methyl]-3-(4-hydroxyphenyl)-5-oxo-, methyl ester, (2R)-

Molecular formulae: 

C24H24O7

Molecular weight: 

424.44

Chem abstract number: 

87414-49-1

Literature reference: 

Studies on the metabolic products of Aspergillus terreus. III. Metabolites of the strain IFO 8835. (1). Kiriyama, Noriki; Nitta, Keiichi; Sakaguchi, Yoshiaki; Taguchi, Yasuhisa; Yamamoto, Yuzuru. Chemical & Pharmaceutical Bulletin (1977), 25(10), 2593-601. Cancer and cell cycle inhibitor. A specific inhibitor for cdc2 family kinase. Kitagawa, Masatoshi; Nishimura, Susumu. Saishin Igaku (1993), 48(3), 418-24.

Toxicity: 

Cell cycle inhibitor

Structure image: 

Aspergillus Species known to produce this metabolite: 

3d image file .c3d (requires Chem3d http://www.cambridgesoft.com/Ensemble_for_Chemistry/ChemBio3D/): 

jmol file (.mol) requires Java to run (http://www.java.com/en/download/help/enable_panel.xml): 


Date uploaded: 

2008-07-07 15:48:31