The Aspergillus nidulans septin AspB localizes to areas of new growth pre- and post- mitotically.

Patrick J. Westfall and Michelle Momany

Author address: 

University of Georgia, Department of Botany, Athens, GA


The septin family of proteins acts as an organizational scaffolding in areas of cell division and new growth. In the filamentous fungus, Aspergillus nidulans, the septin encoding gene, aspB, produces protein that localizes to areas of cellular division and new growth both pre and post-mitotically. AspB localizes at the septum post-mitotically with an underlying polarity evident as cytokinesis progresses. This localization at the septum is dependent on actin, and occurs before the crosswall starts to form. AspB also localizes to areas of new growth including secondary germ tubes and branches. AspB localizes pre- mitotically as a ring at sites of secondary germ tube emergence and branching and is the only known branch site marker. Localization to the secondary germ tube and new branch points is transient, and disappears as the hypha extends. In addition, AspB is found at several stages during the development of the asexual reproductive structure, the conidiophore. It localizes transiently to the vesicle/metulae and metulae/phialide interface, and persistently to the phialide/conidiospore interface

abstract No: 


Full conference title: 

21st Fungal Genetics Conference
    • Fungal Genetics Conference 21st (2000)