Antimicrobial Management Program: Continual Cost Savings at a Large Teaching Medical Center


Author address: 

1Univ of Maryland School of Medicine, Baltimore, MD, 2Univ of Maryland Medical Center, Baltimore, MD.


Background: Increasing antimicrobial use, cost and resulting resistance are major problems in hospitals today. This communication describes the continued effectiveness of one large teaching medical center’s response to that crises Methods: In early 2001, an antimicrobial management program was initiated. The program consisted of 1) a simplified method for obtaining restricted antimicrobials, the "œBUGS" beeper 2) an antimicrobial team consisting of a pharmD and infectious disease attending for real time monitoring of antimicrobial use with active intervention when necessary and 3) the development of key guidelines and policies for antimicrobial prescribing. Results: The cost savings for FY02 (July 1, 01 June 30, 02) after it was implemented compared to FY01 before and during implementation was $1,284,357. The majority of this initial savings was for antifungal agents, $784,195 (21% reduction) but antibacterial antimicrobials were decreased by $486,050 (14%). Since that time, utilization costs have decreased by an additional $823,333 in FY03 compared to FY02 and for FY04 to date (through March 04) compared to FY03 another $898,065 was saved. For these last two fiscal years, almost all of the savings resulted from management of the antifungal agents. Amphotericin B products and fluconazole were reduced but voriconazole particularly by the oral route has increased during this time. Although the reduction in antifungal agents occurred throughout the medical center, it was most prominent in the Cancer Center. Conclusion: An antimicrobial management program with specific active participation by members in high use areas such as the Cancer Center can be invaluable in initial and ongoing antimicrobial cost reductions

abstract No: 


Full conference title: 

42nd Annual Meeting Infectious Diseases Society of America
    • Infectious Diseases Society of America 42nd