Antimicrobial actvity of Nauclea lotifolia(African peach) crude extracts against some pathogenic microorganism.

Isah Legbo Muhammad, Bekeh Agnes Ashabukwuo

Author address: 

1Ibrahim Badamasi Babangida University, lapai, Lapai, Niger state, Nigeria, 2Ibrahim Badamasi Babangida University, lapai, Lapaiu, Niger state, Nigeria


The phytochemical screening and antimicrobial activity of Nauclea  lotifolia fruit, leaf and stem-bark extracts at various concentration of (20.0,10.0, 5.0,and 2.5 mg/ml) were evaluated against some pathogenic microorganisms such as Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Staphylococcus aureus, Aspergillus niger and Candida albicans. The antimicrobial activity was assayed using agar well diffusion method. The result obtained show appreciable inhibitory effort of acetone, aqueous and methanolic extracts of Nauclea lotifolia. However , result obtained was less active compared to that of the control antibiotic (Ciprofloxacillin). The minimum inhibitory concentration (MIC) was determined using serial doubling dilution method and ranged from 5.0-10.0mg/ml, while the minimum bactericidalconcentration (MBC) was determined by plating various dilution of extracts without turbidity and the result  ranged from 5.0-7.5mg/ml. The phytochemical screening revealed the presence of alkaloid, anthraquinones, flavonoids, resin, steroid and saponin. The activity of the plant extract therefore justify their utilization in the treatment of various ailments associated with the test organism.


abstract No: 


Full conference title: 

Microbiology Society Annual Conference
    • MS 2016