Alternaria-induced asthma9734;

Robert K. Bush, MDa, Jay J. Prochnau, MDb

Author address: 

a Department of Medicine, University of Wisconsin Medical, Madison, Wis, USA b William S. Middleton VA Hospital, Madison, Wis, USA


Abstract Acute, severe asthma attacks can be precipitated by a variety of stimuli including exposure to aeroallergens, viral respiratory infections, pollutants, and occupational chemicals. Alternaria is a major aeroallergen in many parts of the world. Sensitivity to Alternaria has been increasingly recognized as a risk factor for the development and persistence of asthma, asthma severity, and potentially fatal asthma exacerbations. We present the case of a patient with IgE-mediated sensitivity to Alternaria who developed an acute, life-threatening asthma attack during the peak Alternaria season. We describe the aerobiology, pathophysiobiology, diagnosis, and treatment options for patients with Alternaria-induced asthma. Keywords: Alternaria, asthma, allergens, aerobiology Abbreviations: FEF2575, Forced expiratory flow rate between 25% and 75% of vital capacity, Heliox 70/30, Helium 70%, oxygen 30%, NaCl-HSA, Sodium chloridehuman serum albumin

abstract No: 

Page 227-234

Full conference title: 

2004 American Academy of Allergy, Asthma, and Immunology Annual Meeting
    • AAAAI 2004 (60th)