Airborne diffusion of Pneumocystis

Anne TOTET, Céline DAMIANI, Firas CHOUKRI, Solène Le GAL, Jean MENOTTI, El Mouktar ALIOUAT, Eduardo DEI CAS, Gilles NEVEZ

Author address: 

Laboratoire de Parasitologie et Mycologie, CHU d’Amiens ; EA 4285, Université de Picardie Jules Verne, Amiens.

Abstract: 

Pneumocystis jirovecii is responsible for a disease affecting immuno-depressed patients: Pneumocystis pneumonia (PCP). Airborne transmission of Pneumocystis has been demonstrated in animal models and is highly probable in humans. However, information concerning burdens of Pneumocystis jirovecii in exhaled air from infected patients is lacking due to the technical limitations of the current sampling methods. This fungus is indeed not cultivable, so impaction method based on the cultivability of microorganisms cannot be used. Also, the difficulties of extraction from a solid support or the lengthy conditions of sampling (filtration technique) let us to consider alternative methods that would be suitable for both sampling and quantifying P. jirovecii in air. Our objective is to evaluate P. jirovecii air diffusion in patients with Pneumocystis pneumonia with Coriolis air sampler sampling combined with RT-PCR assays. Key words: Pneumocystis, airborne diffusion, hospital infection, fungal contamination.
2013

abstract No: 

NULL

Full conference title: 

Aerobiology Symposium 2013
    • AS, 2013