Susceptibility profile of deep-seated yeasts isolates from a university hospital in the northern region of Portugal

Ref ID: 17753

Author:

I. Faria-Ramos*, J. Santos-Antunes, S. Costa-de-Oliveira,
A.G. Rodrigues, C. Pina-Vaz

Author address:

(Porto, PT)

Full conference title:

22nd European Congress of Clinical Microbiology and Infectious Diseases

Abstract:

Objectives: An observational study was conducted at the biggest
hospital in Portugal, aiming to evaluate the susceptibility profile of
yeasts isolated from invasive fungal infections and relevant
epidemiological data.
Methods: Between September 2010 and 2011, all yeasts isolated from
invasive fungal infections admitted at the university hospital S. João, in
Porto, were collected. All strains were identified using Vitek2 system
and the antifungal susceptibility profile was determined according to
CLSI M27-A3 protocol regarding eight antifungals. Clinical and
demographic data were registered. Mortality attributed to fungal
infections was calculated. Chi-square test and multivariable logistic
regression were used to analyze data.
Results: The incidence of invasive infections was 3.2 per 1000
admissions. One hundred and forty six isolates were collected, from
blood (61.5%), peritoneal liquid (29.5%), cerebrospinal fluid (6.4%)
and pleural effusion (2.6%) cultures. Fifty-two percent corresponded to
Candida albicans, followed by C. glabrata (15.2%), C. parapsilosis

Abstract Number: NULL

Conference Year: 2012

Link to conference website: NULL

New link: NULL

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