Risk factors for Candida infections in a neurology intensive care unit: a case-control study

Ref ID: 17738

Author:

C. Bulut*, Y. Kurtoglu Gul, C. Ataman Hatipoglu, S. Yagci,
A.P. Demiro¨

Author address:

na

Full conference title:

22nd European Congress of Clinical Microbiology and Infectious Diseases

Abstract:

Objectives: Candida species has an emerging importance in intensive
care units (ICU) in recent years. The aim of this study was to describe
the epidemiologic and microbiologic characteristics as well as the risk
factors for Candida infections in the neurology ICU (N-ICU).
Methods: All adult patients who were hospitalized over 48 hours in
the N-ICU between 1st January 2010 and 30th October 2011were
included into the study. Patients group was composed ofall patients
with proven Candida infection. Control group comprised of other ICU
patients who didn’t have any Candida infection at all. For the statistical
evaluation, the first Candida attack of infection was selected for each
patient. Identification and antifungal susceptibility of Candida species
was performed by VITEK II system (Biomerieux, France). CDC
criteria’s were used for the definition of hospital infection (HI).
Results: During the study period a total of 693 patients were
hospitalized into the N-ICU. The patient day was 6170 days. Two
hundred and ninety one HI were detected in 137 patients. HI rate was
42.0 per 100 patients and HI density was 47.2 per 1000 patient days.
The control group comprised of 243 patients. Fifty-seven Candida
strains were islated in 44 patients Among isolates, 11 C. albicans, 8 C.
tropicalis, 31 C. parapsilosis, 5 C. glabrata, and 2 C. krusei. Twenty
two of all Candida infections were catheter related bloodstream
infections while remaining were urinary tract infections. When patient
and control groups were compared, older age; having any of the
following: nasogastric tube, central venous catheter, arterial catheter,
enteral feeding and parenteral feeding were found as risk factors for

Abstract Number: NULL

Conference Year: 2012

Link to conference website: NULL

New link: NULL

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