Results from the China Hospital Invasive Fungal Surveillance Net 2009-2010: an analysis of susceptibilities of yeast species to fluconazole and voriconazole as determined by CLSI standardised disc diffusion

Ref ID: 17719

Author:

H. Wang*, M. Xiao, Y. Xu

Author address:

(Beijing, CN)

Full conference title:

22nd European Congress of Clinical Microbiology and Infectious Diseases

Abstract:

Objectives: We reported the results of China Hospital Invasive Fungal
Surveillance Net (CHIF-NET) 2009-2010, aiming to illustrate the
species distribution and antifungal susceptibilities of yeast isolates
collected.
Methods: CHIF-NET is the first nationwide invasive fungal infection
surveillance study in China that covered 12 tertiary hospitals in nine
provinces. It is important to note that, only yeasts that isolated from
blood or other sterile body sites were collected. All isolates were
identified by amplification and sequencing of the internal transcribed
(ITS) region. Antifungal susceptibility testing to fluconazole (FLC) and
voriconazole (VOC) were performed using disk diffusion method
according to CLSI document M44-A.
Results: Overall, a total of 814 yeast isolates were collected, which
were assigned to 27 species. Candida species accounted for ~90% of all,
followed by Cryptococcus species (8%) and Trichosporon species (1%).
Within Candida genus, C. albicans the predominant (34%), followed
by C. parapsilosis (18%), C. tropicalis (15%), C. glabrata (11%), C.
metapsilosis (3%), C. krusei (2%), C. guilliermondii (2%) and other
Candida spp. (2%).

Abstract Number: NULL

Conference Year: 2012

Link to conference website: NULL

New link: NULL

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