Pulmonary mucormycosis. Findings in high resolution computerized tomography: experiences from a Vietnamese tertiary hospital

Author:

NTB Ngoc1,2*, LN Huy1, P Michel3

Author address:

1Fungal Infections Center, Vietnam National Lung Hospital, Hanoi, Vietnam

2Lung Department, University of Medicine and Pharmacy, Hanoi, Vietnam

3Medical Center, The University of Munich, Munich, Germany

Full conference title:

10th Advances Against Aspergillosis and Mucormycosis

Date: 2 February 2022

Abstract:

Purpose:

Mucormycosis, a rare fungal infection has recently been diagnosed more frequently, also in relation with Covid-19. Pulmonary mucormycosis, (PM) its second most common form is associated with an overall fatal rate over 50%(Feng & Sun, 2018). Currently, the diagnosis of PM relies on radiological and histopathological findings. Even though radiologic findings can be non-specific, they can have distinguished features and are important to guide surgical biopsies for histopathological examinations. Here, we present the radiological findings of 6 mucormycosis cases seen in our hospital from January 2020 to September 2021 with emphasis on observations from High Resolution CT scans (HR-CT).

 

Methods:

We conducted an observational retrospective study for all mucormycosis cases treated in Vietnam National Hospital in appropriate time.

 

Results:

All 6 cases showed damages to the lower- middle lobe more frequently seen at the left side than the right. The most common lesion was consolidation (ground glass opacity at the early stage then changing to nodules and masses (i.e.necrotizing forms) with very large cavities developing with or without air-fluid levels. Pulmonary artery enlargement and pseudoaneurysms were seen in 2 cases associated with massive hemoptysis requiring embolization and lobectomy.

 

Conclusion:

We present high quality radiological findings in PM are not fundamentally different from those seen in other fungal infections such as aspergillosis, yet appear more massive . HR-CT scans can help to locate the involved site precisely and this information may be used as predictive factor for hemoptysis. Biopsy procedure remains the instrument of choice for prompt diagnosis and treatment.

Abstract Number: 8

Conference Poster: 008

Conference Year: 2022

Link to conference website: https://aaam2022.org/

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