Prevalence of Candida species in the gastro-intestinal tract of humans

Ref ID: 19620

Author:

R. Someshwaran*, B. Appalaraju and A. C. Baskkaran

Author address:

Department of Microbiology, PSG Institute of Medical Science and Research, Coimbatore-641 004

Full conference title:

Society for Indian Human and Animal Mycologists 2014

Date: 10 January 2014

Abstract:

vaginal thrush and also highly invasive fungal infections with high morbidity and mortality. The ARTEMIS Global Antifungal
Surveillance Program showed that C. albicans was the most common (63-70%) candidal cause of invasive fungal infections,
followed by C. glabrata (44%), Candida tropicalis (6%), and Candida parapsilosis (5%). The aims and objectives of the
present study was to determine the prevalence of Candida species in gastrointestinal tract and to evaluate the antifungal
susceptibility patterns of Candida species. Atotal of 61 stool samples (Stool samples of master health check-up patients sent for
culture and sensitivity) were collected between September 2013 to October 2013 and processed using Blood agar, Sabouraud’s
dextrose agar, Germ tube tests (by Trypticase Soy Broth and Serum), sugar fermentation and assimilation tests. They were also
subjected to Tetrazolium Reduction Media, Himedia CHROM agar, VITEK-2 identification system and MALDI ToF analysis
for further identification. Antifungal susceptibility tests were also performed. In the present study, stool sample from patients
with complaints of gastrointestinal tract, patients receiving antibiotics and patients with HIV/Immunosuppressed/AAD were
excluded. It was found that Candida albicans (32%) and Candida tropicalis (23%) were the predominant species obtained out
of 61 stool samples. Rare species like Candida norvegensis, Candida lambica, Candida robusta were also identified. Further,
there were discrepancies between various systems of Candida identification. We still find pooled human serum is better than
Trypticase soy broth for performing Germ tube tests. 9.8% and 8.1% of the Candida isolates were resistant to fluconazole and
itraconazole respectively. In conclusion, Candida albicans and Candida tropicalis are the most commensals of gastrointestinal
tract of the humans.
9830;Corresponding author
E-mail:drsomeshwaran@gmail.com

Abstract Number: OP-001

Conference Year: 2014

Link to conference website: http://www.siham2014.com

New link: NULL

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