Positive microbiology findings in non-cystic fibrosis bronchiectasis and co-morbidities

Zoran Arsovski, Biserka Kjaeva, Dejan Dokic, Zlatica Goseva, Sava Pejkovska, Elena Janeva, Suzana Arbutina, Angela Debreslioska, Anita Arsovska

Abstract: 

Background: Bronchiectasis are becoming a focus of the respiratory scientists in recent years.

Aim of the study: To assess microbiology findings in non-cystic fibrosis bronchiectasis (non-CFB) and frequency of associated co-morbidities.

Material and methods: We analyzed 172 patients with non-CFB as a primary diagnosis that were hospitalized during a period of 61 months.

Results: Positive microbiology analysis was obtained in 26,74% of the patients. 14,53% of the patients had positive results on Candida albicans. The most frequent pathogen found in sputum was Pseudomonas aeruginosa (5,81%). In 3,48% Acinetobacter species was found and E. Coli and Haemophyllusinfluenzae were both found in 1,74 % of the patients. Other findings were Streptococcus pyogenes, Streptococcus pneumoniae, Enterobacter aerogenes, Klebsielapneumoniae, Aspergillus niger, Aspergillus fumigatus, Stenotrophomonas maltophilia etc. In 5,23% of patients coexistence of Candida albicans with other bacterial pathogens was found. 56,66% of the non-CFB patients with positive pathogen findings had chronic respiratory insufficiency. COPD coexisted with non-CFB in 26,66% of the patients with positive pathogen microbiology findings. Co-existence of non-CFB with other co-morbid conditions were found (i.e Kartagener Syndrome, Wegener's granulomatosis, Alcoholism, Myelodysplastic Syndrome, Esophagotracheal fistula etc). Appropriate drug treatment was carried out in all patients and one patient with esophagotracheal fistula was transferred to Surgery for consecutive treatment.

Conclusion: Mayor part of fungal findings represent only colonization. Management of non-CFB should consider other co-existingdiseases and patient's condition.

2016

abstract No: 

PA2558

Full conference title: 

European Respiratory Society 2016
    • ERS 26th (2016)