Mycological profile of fungal sinusitis : a retrospective study over a 7-year period in a tertiary care hospital in Riyadh , Saudi Arabia

Ref ID: 19573

Author:

AM Albarrag1*

Author address:

1Dept. of Pathology (32), College of Medicine, King Saud University, Riyadh, Saudi Arabia

Full conference title:

6th Advances Against Aspergillosis 2014

Abstract:

Purpose:
Fungal rhinosinusitis (FRS) includes a wide spectrum of fungal diseases ranging from colonization
and mildly symptomatic to invasive and fatal disease. The fungi causing FRS have a great diversity
and regional variation in the incidence has been reported.
Our aim was to look at the mycological profile and clinical aspects of fungal sinusitis in a tertiary
hospital in Riyadh, Saudi Arabia.
Methods:
This is a retrospective study conducted on samples submitted to the clinical mycology laboratory
from 2005 to 2011. Samples including sinus secretions, and tissue specimens were processed and
examined by direct microscopy and microbiology culture
Results:
562 suspected patients were included in the study with a total number of 1362 samples. Samples
per patient ranged from 2-9 samples. Male to female ration was 1.4: 1. A total of 138 (24.6%)
were positive for fungal hyphae by direct microscopy examination and 129 (23%) were positive by
culture. Out of 138 patients with positive culture, 71.3% were allergic fungal sinusitis cases. Nasal
tissues were positive for fungal element in 26 patients (18.8%). Aspergillus species were the most
common fungi isolated (77.5%) mainly A. flavus (79%). Bipolaris species were ranked second with
22.4%.
Conclusion:
In this study, the fungi associated of fungal sinusitis were different than that of western countries.
Allergic fungal sinusitis was the most common type. sp was the most common causative agent in
both allergic and invasive forms of the disease.

Abstract Number: 99

Conference Year: 2014

Link to conference website: http://www.AAA2014.org

New link: NULL


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