Galactomannan antigen assay from bronchoalveolar lavage fluid in diagnosis of invasive pulmonary aspergillosis in intensive care units patients

Ref ID: 19549

Author:

F Khorvash1, M Meidani1, L Babaei1, S Haghighipour1*, S Abbasi2, B Ataei1, M Yaran1,
Z Karami Saravi3

Author address:

1Department of Infectious Diseases, Infectious Diseases and Tropical Medicine Research Center, Isfahan
University of Medical Sciences, Isfahan, Iran
2Department of Anesthesiology, Isfahan University of Medical Sciences, Isfahan, Iran
3Department o

Full conference title:

6th Advances Against Aspergillosis 2014

Abstract:

Purpose:
Invasive pulmonary aspergillosis (IPA) is an important infection in critically ill patients including
patients of intensive care units (ICU). Different diagnostic tools are available and since its mortality
is high, it is vital to start the antifungal therapy as soon as possible. Knowing the epidemiology of
this disease in each ICU and area will help to better and more rapid management of such patients.
The aim of this study is to determine the frequency of IPA based on the level of galactomannan in
bronchoalveolar lavage fluid in ICU of Al-Zahra hospital, Isfahan, Iran.
Methods:
This was a cross sectional study, which was conducted in Al-Zahra hospital, Isfahan, Iran, between
2010 to 2011. The study population was all the patients admitted to ICU and were suspected to have
invasive Aspergillus spp pneumonia. The level of galactomannan in bronchoalveolar lavage was
measured and demographic data were gathered by the questionnaire.
Results:
The frequency of IPA in this study was calculated as 2.43% while galactomannan level in
bronchoalveolar lavage fluid of this patient (2.50) was significantly higher than others (0.03±0.02).
Conclusion:
Larger studies are required to determine the exact frequency of IPA and the best antifungal therapy
for it.

Abstract Number: 76

Conference Year: 2014

Link to conference website: http://www.AAA2014.org

New link: NULL

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