Diabetes mellitus and 30-day and 90-day mortality after hospitalization with pneumonia: a population-based follow-up study of 41 793 adult patients

Ref ID: 5689

Author: R.W. Thomsen, J. Brommann, A. Riis, H.-H. Lervang, H.C. Schønheyder, H.T. Sørensen

Author address:

Aalborg, Aarhus, DK

Full conference title:

16th European Congress of Clinical Microbiology and Infectious Diseases

Abstract:

Objectives: Diabetes may be associated with increased mortality after pneumonia due to decreased
immunity, impaired lung function, and hyperglycaemic derangement. We examined diabetes as a predictor
of 30-day and 90-day mortality in a large cohort of adult patients hospitalized with pneumonia.
Methods: Population-based cohort study in the three Danish counties of North Jutland, Viborg and
Aarhus between 1994 and 2003. Patients with a first-time hospital discharge diagnosis of pneumonia were
identified in hospital discharge registries. Information on diabetes and comorbidities was obtained from
discharge registries and prescription databases. All patients were followed for 90 days after hospitalization
through the Danish Civil Registration System. We compared mortality rates in patients with and without
diabetes, adjusted for gender, age, and comorbidity.
Results: A total of 41 793 adult patients were hospitalized with pneumonia (median age 74 years); of
these, 3928 patients (9.6%) had diabetes. Overall mortality in diabetic patients compared with other
patients with pneumonia was 18.7% vs. 14.8% after 30 days, and 26.5% vs. 21.4% after 90 days. After
adjustment, mortality rates in patients with diabetes were only marginally increased (mortality rate ratio =
1.12 (95%CI: 1.04-1.21) after 30 days, and 1.09 (95% CI: 1.02-1.16) after 90 days) compared with nondiabetic
pneumonia patients.
Conclusion: Our results corroborate previous reports suggesting that diabetes has only a very limited
influence on outcome in patients hospitalized with pneumonia.

Abstract Number: O121

Slides: y

Conference Year: 2006

Link to conference website: NULL

New link: NULL


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