Comparative analysis of Aspergilli to facilitate novel strategies in fungal biotechnology

Ref ID: 18259

Author:

RP de Vries(1), E Majoor(1), A Wiebenga(1), J Houbraken(1), P Dyer(2), PA vanKuyk(1,3), J Wortman(4), S Baker(5), I
Grigoriev(6)

Author address:

(1)CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands; (2)School of Biology, University of Nottingham,
UK; (3)Molecular Microbiology, Leiden University, The Netherlands; (4)Broad Institute, Cambridge, MA, USA; (5)Pacific Northwest
Nat

Full conference title:

Asperfest 9

Abstract:

Aspergillus is not only one of the most important fungi in biotechnology, it is also one of the most commonly found groups of fungi in
environments worldwide and one of the most severe opportunistic human pathogens. Due to this, Aspergillus has one of the largest
research communities in the fungal field. This has resulted in it being one of the most intensively studied fungi with respect to
genomics. The availability of >10 genomes in combination with the tools developed for Aspergillus genomics (e.g. AspGD and
CADRE) enables comparative genomics at a high level. In 2011 the JGI approved sequencing of an additional 8 Aspergilli and
Penicillia, to advance comparative genomics in these fungi. This project include more industrial species, but also species distantly
related to those for which genome sequences are already available. A large consortium of researchers has been established to perform
comparative genomics on the new and already available Eurotiales genomes (32 in total). In addition, this analysis will be supported
with experimental data to validate the differences found through bioinformatics. Details on the project and current status will be
presented.

Abstract Number: 4

Conference Year: 2012

Link to conference website: NULL

New link: NULL

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