Clinical management and outcome of childhood lung abscess (LA): A 15-year experience

Ref ID: 18405

Author:

Oleksander Katilov, Dmytro Dmytriiev, Oleksander Mazulov.

Author address:

Pulmonology,
Vinnitsa National Medical University, Vinnitsa, Ukraine

Full conference title:

European Respiratory Congress

Abstract:

In order to evaluate the clinical manifestations, management and outcome of childhood
LA, a retrospective chart review of 35 pediatric with LA from Semtember
1995 to Semtember 2010 was conducted. Among the 37 patients (20 males and
15 females), 51, 4% (18/37) were primary lung abscess and 49,6% (17/35) had
underlying chronic diseases (secondary lung abscess). The predisposing factors of
the primary group (n = 18) included 16 cases of respiratory tract infection and 2
with laceration wound. The underlying diseases in the secondary group (n = 17)
included 11 cases of hematologic disorder (64,7%), 4 of congenital heart disease,
and 2 each of hyperimmunoglobulin E syndrome. 14 patients underwent diagnostic
tapping, including echo-guided aspiration (11 cases) and computed tomographyguided
percutaneous needle aspiration (2 case). Positive yield rate from aspiration
of lung abscess was 50% (7/14). Surgical intervention was performed in 10 of the
secondary group and in 1 patient from the primary group. The pathogens were
identified in 17 patients (49,6%): 5 with oral flora, 4 with Staphylococcus aureus
plus other pathogens, 1 with S. aureus alone, 2 with Pseudomonas aeruginosa plus
Proteus mirabilis, 4 with P. aeruginosa alone, and 1 with Aspergillus. The average
duration of parenteral antibiotic use was 20 days. 2 cases (5.4%) died due to poor
control of the underlying diseases, and 4 of the patients (10,8%) had sequelae (3
with bronchiectasis and 1 with lung fibrosis). Early percutaneous aspiration has an
important role in identification of pathogens. Oral anaerobes and S. aureus are the
core pathogens in primary lung abscess and gram-negative pathogens should also
be considered in secondary LA.

Abstract Number: P1156

Conference Year: 2011

Link to conference website: http://www.ers-education.org/ersMade/abstract_print_11/files/Abstract_book_2011.pdf

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