Ref ID: 17740
Author:
R. Patel*, B. Saberwal, S. Quan, A. Gonzalez-Ruiz
Author address:
(London, UK)
Full conference title:
22nd European Congress of Clinical Microbiology and Infectious Diseases
Abstract:
Objectives: To provide a picture of local epidemiology and to assess
whether appropriate antifungal therapy is administered in a timely
fashion. To evaluate risk factors, outcome and the associated costs.
Methods: Retrospective analysis of all candidaemias between January
2005 and December 2010 at a 460 bed district general hospital.
Results: There were a total of 60 candidaemias between 2005-2010
resulting in a prevalence of 0.24 per 1000 patient admissions. The most
predominant species were C. albicans which accounted for 43 cases
(73%). From a total of 60 candidaemias, 55 cases were investigated
further. It was found that 56% of cases were diagnosed in intensive care
(ITU) resulting in ITU prevalence of 9.4 per 1000 admissions compared
to a non ITU prevalence of 0.10 per 1000 admissions. This equates to
approximately a 100-fold difference between ITU and non ITU cases,
consistent with previous reports. The most common risk factor was a
central venous pressure line (67%). Forty out of 45 (88.9%) patients
received appropriate antifungal treatment within 24 hours of positive
blood culture.
From a total of 54 candidaemias, crude mortality rate was 36.6% (15/
41) and 46.2% (6/13) for C. albicans and non-albicans Candida
respectively. The difference between the crude mortality is 9.6% and is
not significant (p = 0.75, Fisher’s exact test). Hospitalization plus
antifungal costs were ≤48 698/pt and ≤67 809/pt for the C. albicans and
non-albicans Candida groups respectively. The average length of stay
per patient was 58 bed days however, the C. albicans group accounted
for 18.6 bed days/pt in ITU and 34.5 bed days/pt in non ITU wards,
compared to the non-albicans Candida group who accounted for 23.8
bed days/pt in ITU and 50.7 bed days/pt in non ITU wards.
Conclusions: 88.9% of patients received timely antifungal treatment.
There is a high mortality rate in patients with candidaemias. The care of
C. albicans infections was on average ≤19 111/pt cheaper. Trust
outcome would be to devise and implement a candidaemia score card to
improve outcomes and costs.
Abstract Number: NULL
Conference Year: 2012
Link to conference website: NULL
New link: NULL
Conference abstracts, posters & presentations
-
Title
Author
Year
Number
Poster
-
v
C Gutierrez Perez1*, S Dhingra1,2, SM Kwansy3, TJ Opperman3, RA Cramer1
2022
93
-
v
PC Chatterjee1*, WC Chiu1, EBB Burgener2, PLB Bollyky3, JH Hsu1
2022
92
-
v
AS Serris1*, FU Uhel2, GMB Martin-Blondel3, OL Lambotte4, MEB Bougnoux5, EL Litvinova6, AO Ouedrani7, CR Rouzaud1, VB Bedarida8, JHR Raphalen9, FL Lanternier1,10
2022
91
-
v
ZA Lewis1, RB Meagher2*, S Ambati2, X Lin1
2022
90
-
v
QJ Choudhury1*, S Ambati2, X Lin1, ZA Lewis1, RB Meagher2
2022
-
v
M James1*, KW Liu1, E Vesley1, T Hohl2, RA Cramer1
2022
88
-
v
D Luptakova1, RH Patil1,2, V Havlicek1,2*
2022
87
-
v
EI Matthaiou1*, W Chiu1, C Conrad2, J Hsu1
2022
86
-
v
H Kamboj*, M Vijay, L Gupta, P Vijayaraghavan
2022
85
-
v
S Hartung1,2*, TNM Hoang1,2*, Z Cseresnyes3*, N Schuck1, K Rennert4,5, F Klos6, AS Mosig5,7, MT Figge3,8, M von Lilienfeld-Toal1,2
* Authors 1, 2 and 3 contributed equally
2022
84
