Burden of serious fungal infections in Mongolia

Ref ID: 19397

Author:

B. Lkhagvaa,1 Z. Deleg2 and D. W. Denning3

Author address:

1Ach Medical Institute, Ulaanbaatar, Mongolia; 2Health Sciences
University of Mongolia, Ulaanbaatar, Mongolia and 3The
University of Manchester, in association with the LIFE program,
United Kingdom

Full conference title:

6th Trends in Medical Mycology 2013

Date: 11 October 2014

Abstract:

Introduction Mongolia has a geographically dispersed population
across a large land-locked area in North East Asia. As no serious
attempt has been made to estimate the number of serious fungal
infections in Mongolia previously, we have attempted this, based on
at risk population data and published rates.
Methods A full literature search was done to identify all epidemiol-
ogy papers reporting fungal infection rates from Mongolia. We used
specific populations at risk and fungal infection frequencies in the
population to estimate national incidence or prevalence. The statisti-
cal yearbook of Mongolia statistics of 2011; the 2011/12HIV infec-
tion and AIDS rates from the HIV/STI Research and Surveillance
Department NCCD, WHO TB statistics, 2011; COPD rates from report
Prevalence and future approach for prevention and control of Respi-
ratory Diseases; Asthma prevalence was from Vinnanen et al,
Allergy, 2005.
Results The Mongolian population is about 2.8 million with 41%
under 15 years of age. Estimates are: 5% of women (age 15-
50 years) get 4 episodes or more of Candida vaginitis per year, a
total of 40,347 annually. HIV/AIDS population is low at an esti-
mated 127 infected people, 64% not on ARV therapy with 19 new
AIDS cases annually and 17 deaths. The rate of Pneumocystis pneumonia (and cryptococcal meningitis) appears be very low at 1%.
There were 4,256 pulmonary TB cases (all but 5 in HIV negative
people) resulting in prevalence of 590 cases of chronic pulmonary
aspergillosis, using a 15% annual mortality rate, perhaps 50% of the
total CPA case load, estimated at 1,181 patients. The prevalence of
asthma among adults is low at 1% (weighted mean) ~16,589 people
and assuming 2.5% have ABPA415 cases would be expected, and
547 SAFS cases. COPD is common with an estimated 87,162 cases,
and assuming a 7% admission rate, 6,101 admissions and 79 cases
of invasive aspergillosis in COPD. Assuming a low rate of candida-
emia of 5/100,000 141 cases are anticipated and 21 cases of can-
dida peritonitis in surgical patients, among the 24,500 abdominal
surgeries annually. Tineacapitis and fungal keratitis were difficult to
estimate and probably uncommon.
Conclusion Serious fungal infections in Mongolia are dominated by
recurrent candida vaginitis and allergic and chronic aspergillosis.
These basic estimates require epidemiological studies to validate or
modify the substantial burden estimates.

Abstract Number: p112

Conference Year: 2013

Link to conference website: NULL

New link: NULL

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