Burden of fungal infections in Morocco

B.E. Lmimouni1 , S. Azelmat2 , C. Hennequin3 , D. Denning4

Author address: 

1School Of Medicine And Pharmacy, University Mohamed The Fifth, Parasitology and Medical Mycology Lab, Military Teaching Hospital Mohamed the Fifth, Hay Riad, Rabat, Morocco, 2Parasitology And Medical Mycology, Military Teaching hospital Mohammed the Fifth, Rabat, Morocco, 3Parasitology-mycology, APHP, Hôpital St Antoine, Paris, France, 4University of Manchester, Manchester, United Kingdom

Abstract: 

Objectives: We report for the first time in Morocco burden estimates of fungal infections. The aim of this study was to estimate the incidence and prevalence of fungal infection in Morocco.

Methods: We used the national demographic data and performed a PubMed and Scopus search to retrieve all published papers on fungal infections from Morocco. We have also modelled the likely burden of serious fungal infections using methodology previously published by LIFE.

Results: We report for the first time the main causes of these diseases in our country. Superficial mycoses and dermatophytic infection (onychomycosis, tinea capitis, others …) are very commonly diagnosed, We have found 13,294 cases in the published papers. Deep fungal infection are less found in the literature. Modlelling shows higher rates for all infections where modelling is possible, especially for pulmonary fungal infections. Literature Modelling Infection Rate/100,000 Total burden Rate/100,000 Total burden Cryptococcal meningitis 0.32 115 0.7 252 Pneumocystis pneumonia 0.22 78 1.2 420 Invasive aspergillosis 0.88 315 1.9 674 Mucormycosis 0.01 4 0.2 72 Chronic pulmonary aspergillosis post TB 0.74 266 8.6 3085 Allergic bronchopulmonary aspergillosis (ABPA) 0.01 4 51 18,400 Severe asthma with fungal sensitization (SAFS) 0.28 100 67 24,292 Candidaemia 1.47 528 5 1800 Oral Candidiasis 0.25 90 22 7800 Mycetoma 0.11 40 Recurrent Candida vaginitis (>4x/year) 0.17 30 2755 496,000 Histoplasmosis 0.01 4 - - Skin dermatophytic infection 13.97 5031 - - Onychomycosis 14.08 5069 - - Tinea capitis 8.87 3194 - - Deep dermatophytosis 0.02 10 - - Total burden estimated 14522 551,400

Conclusion: A focus on improving the diagnosis and epidemiological data related to fungal infection is necessary in Morocco.

2019

abstract No: 

P258

Full conference title: 

9th Trends in Medical Mycology Conference 2019
    • TIMM (2019)