Conference abstracts, posters & presentations

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ECCMID 29th (2019)
Title Author Yearsort ascending No. Poster
First detection of TR34/L98H Aspergillus fumigatus mutants in Switzerland Silvio Ragozzino*1, Daniel Goldenberger2, Stefan Zimmerli3, Konrad Mühlethaler4, Dionysios Neofytos5, Arnaud Riat6, Katia Boggian7, Nolte Oliver 8, Anna Conen9, Hans Fankhauser10, Frederic Lamoth11, Nina Khanna1 2019 P2170
Invasive pulmonary aspergillosis after heart transplantation: a 7-year single-centre experience Karina Monosova*1, Maria Simonenko1, Ksenia Zagorodnikova1, Petr Fedotov1, Yulia Sazonova1, Rubinchik Vadim1, Mikhail Karpenko1 2019 P0156
Mould surveillance at a tertiary university hospital documents increasing azole resistance in Aspergillus among Danish cystic fibrosis patients Malene Risum*1, Helle Krogh Johansen2,3, Raluca Datcu1, Rasmus Krøger Hare1, Karin Meinike Jørgensen1, Maiken C. Arendrup1,2,3 2019 O1124
Isavuconazole kinetic exploration for clinical practice Lea Darnaud1, Fabien Lamoureux2, Cendrine Godet3, Sabdrine Pontier4, Alexa Debard5, Nicolas Venisse3, Pauline Martins3, Didier Concordet6, Peggy Gandia*6,1 2019 O0737
Evaluation of DermaGenius, a multiplex real-time PCR to identify dermatophytes directly from specimens Christina Kuenzli1, Cornelia Ottiger2, Hans Fankhauser2, Michael Oberle*2 2019 P2199
Pulmonary colonisation with moulds and Exophiala dermatitidis in adult cystic fibrosis patients Nelly Daniela Zurita Cruz*1, Arturo Manuel Fraile Torres1, Ayla Yarci Carrión1, Leticia Fontán García-Rodrigo1, Belén Fernández-Caso1, Josefa Barba Almeida1, Rosa M. Girón1, Buenaventura Buendia1 2019 P1109
Use of ibrexafungerp (formerly SCY-078) to treat severe azole-refractory oesophageal candidiasis: a case report from the FURI study Jose Vazquez*1, Aprile Osborn 2019 P0125
In vivo pharmacodynamic evaluation of the novel antifungal agent APX001 in a murine model of invasive pulmonary aspergillosis against wild-type and Cyp51 mutant Aspergillus fumigatus strains Alex Lepak*1, Miao Zhao2, David Andes1 2019 O1066
Protecting the patients from environmental fungal contamination during maintenance works of an haematology ward with laminar airflow system: effectiveness of a set of measures Florence Le Gallou*1, Wiesel Sophie1, Anne-Claire Guille Des Buttes1, Thomas Gaumart1, Véronique Sellin1, Emilie Racine2, Christine Cartier2, Didier Lepelletier1 2019 P2634
First detection of TR46/Y121F/T289A alteration in CYP51A associated with pan-azole resistance in environmental Aspergillus fumigatus isolates in Greece Maria Siopi*1, Olga Rivero-Menendez2, Ana Alastruey-Izquierdo2, Panagiota-Christina Georgiou1, Maria-Ioanna Beredaki1, Athanassios Tsakris3, Spyros Pournaras1, Joseph Meletiadis1,4 2019 O0171
Clinical outcome after exacerbation in cystic fibrosis patients according to their fungal and bacterial microbiota evolution Cecile Angebault*1,2, Louise-Eva Vandenborght3,4, Paul-Louis Woerther1,2, Laurence Bassinet5, Natascha Remus5, Nathalie Fauchet5, Ralph Epaud5, Laurence Delhaes6,4, Françoise Botterel1,2 2019 O0706
Breakthrough invasive fungal infection among patients with haematologic malignancies: a prospective multi-centre study Pedro Puerta1, Cecilia Martin-Gandul2, Jon Badiola3, Marina Machado4, Montserrat Batlle5, Juan Carlos Ramos Ramos6, Ana Fernandez-Cruz7, Lucia Gomez8, Júlia Laporte9, Isabel Ruiz10, Lucrecia Yañez11, Lourdes Vázquez12, Pilar Martín-Dávila13, Lucía Boix Palop8, Celia Cardozo*1, Isabel Sanchez-Romero14, Francesc Marco Reverte15, Alex Soriano1, Miguel Salavert16, Ana Alastruey-Izquierdo17, Jesus Fortun Abete13, Carlota Gudiol9, Julio Garcia Rodriguez6, Jesus Guinea Ortega4, Pedro González3, Manuela Aguilar-Guisado2, Carolina Garcia Vidal1 2019 O0565
Successful Treatment of Two Patients with Candida auris Candidemia with the Investigational Agent, Oral Ibrexafungerp (formerly SCY-078) from the CARES Study Deven Juneja*1, Omender Singh1, Bansidhar Tarai1, David Angulo Gonzalez2 2019 L0028
Urinary microbial metabolite array as an emerging standard for early and non-invasive diagnosis of infectious diseases Radim Dobiáš1, Anton Skriba2, Dominika Luptakova2, Tomas Pluhacek2, Vladimir Havlicek*2 2019 O0268
The management of invasive fungal disease prior to haematopoietic stem-cell transplant and its effects on post-allogeneic fungal infections Sabine Kuster*1, Susanne Stampf2, Bernhard Gerber3, Veronika Bättig1, Maja Weisser1, Sabine Gerull4, Michael Medinger4, Jakob Passweg4, Urs Schranz5, Christian Garzoni6,7, Christoph Berger8, Yves Chalandon9, Nicolas Mueller10, Christian Van Delden11, Dionysios Neofytos11, Nina Khanna1 2019 O0566
Favourable Clinical Outcome of Two Patients with Candida spp Spondylodiscitis treated with Oral Ibrexafungerp (formerly SCY-078) from the FURI Study Philipp Köhler*1,2, Oliver A. Cornely1,2,3, David Angulo Gonzalez4 2019 L0033
In vitro activity of APX001A and comparator agents against 1706 fungal isolates collected during an international surveillance programme (2017) Michael Huband*1, Michael A. Pfaller1, Robert Flamm1, Paul Bien2, Mariana Castanheira1 2019 O0269
Invasive pulmonary aspergillosis in patients with haematological malignancies: 272 episodes in 18 years Galina Klyasova*1, Anna Malchikova1, Elena Parovichnikova1, Sergei Kravchenko1, Valeriy Savchenko1 2019 O0568
The pharmacokinetics of fluconazole in critically ill patients with varying degrees of renal function or that are undergoing continuous renal replacement treatment Eline Muilwijk1, Dylan De Lange2,3, Roeland Wasmann1, Jeroen Schouten1,4, Paul E. Verweij1,5, Peter Pickkers1, David Burger1, Tim Frenzel1, Roger Brüggemann*1,5 2019 O0112
Rezafungin PK/PD in a mouse model of Pneumocystis pneumonia Shawn Flanagan*1, Voon Ong1, Grayson Hough1, Ken Bartizal1, Alan Ashbaugh2, Melanie T. Cushion2 2019 O0271
Performance of 16S rRNA/18S rRNA PCR and amplicon sequencing compared to conventional culture methods for the identification of bacterial/fungal pathogens in diagnostically challenging infections Astrid Muyldermans*1, Kurt Beuselinck1, Katrien Lagrou1, Stefanie Desmet1 2019 O0590
EUCAST susceptibility testing of rezafungin: MIC data for contemporary Danish clinical yeast isolates Karin Meinike Jørgensen*1, Karen Marie Thyssen Astvad1, Rasmus Krøger Hare1, Maiken C. Arendrup1,2,3 2019 O0115
Influenza-associated aspergillosis in critically ill patients in two Swiss centres during the Influenza season 2017/2018: an underestimated and severe complication Frederike Waldeck*1, Filippo Boroli2, Noémie Suh3, Domenica Flury1, Anne Iten3, Laurent Kaiser1, Jacques Schrenzel3, Jerome Pugin2, Gian-Reto Kleger4, Werner Albrich1 2019 O0564
Favorable Response to Oral Ibrexafungerp (formerly SCY-078) in Patients with Refractory Fungal Diseases, Interim Analysis by Pathogen from a Phase 3 Open-label Study (FURI) Oliver A. Cornely*1, Luis Ostrosky-Zeichner2, Rachel Miller3, Andrej Spec4, George Thompson5, Thomas J. Walsh6, Riina Richardson7, Robert Krause8,8, Peter G. Pappas9, Kathleen Mullane10, Caryn G. Morse11, John W. Sanders11, Günter Weiss12, Oliver Witzke13, Jose Vazquez14, Marisa H. Miceli15, Thomas Patterson16, Martin Hoenigl17,8, Barbara Alexander3, David Angulo Gonzalez18 2019 L0010
Antifungal stewardship based on 1,3-beta-D-glucan in critical patients: a tool to rationalise empirical antifungal therapy Valeria Cento*1, Milo Gatti 2, Valentina Lepera 1, Valentina Mancini 3, Ernestina Mazza 4, Carloandrea Orcese 5, Jacopo Colombo 6, Maria Cristina Moioli 5, StefaniaTorri 1, Alessandra Bielli 7, Laura Elisa Gasparini 2, ChiaraSilvia Vismara 7, Paolo Brioschi 2, Massimo Puoti 5, Andrea De Gasperi 4, Roberto Cairoli 3, Carlo Federico Perno 7, Gianluigi Lombardi 7 2019 O0835

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