ptLEM (2): acute IPA, following AML

Submitted by: Michael on: 15 April 2013

Case number: 2


This 69 year old white female with recently diagnosed acute myeloid leukaemia (AML) developed definite pulmonary aspergillosis during her second cycle of chemotherapy. She was diagnosed based on chest CT (subpleural consolidations) and an open lung biopsy showed hyphae in lung tissue. She was refractory to Abelcet (with progression of disease) and itraconazole (abnormal liver function tests). She was treated with caspofungin for 37 days with response.

Species (if applicable): aspergillus spp.

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