A new diphenolic metabolite isolated from the marine-derived fungus Aspergillus niger 102.

Author: 

Zhang PP, Song S, Lang JJ, Jia CX, Yan SJ, Liu L, Chen SH, Li J.
J Asian Nat Prod Res. 2018 Jul 1:1-7

Abstract: 

A new diphenolic derivative asperdiphenol A (1), along with nine known compounds (2-10), was isolated from the marine-derived fungus Aspergillus niger 102. Their structures were elucidated on the basis of spectroscopic analysis including NMR and MS spectrometry. Compound 1 was suggested to be a chiral mixture by the specific rotation and chiral HPLC. Compound 1 was evaluated for its anti-inflammatory, antibacterial, and cytotoxic activity.