Invasive pulmonary aspergillosis associated with marijuana use in a man with colorectal cancer.


Cescon DW, Page AV, Richardson S, Moore MJ, Boerner S, Gold WL.
J Clin Oncol. 2008 May 1;26(13):2214-5


In November 2006, a 65-year-old man presented for routine oncology follow-up with a 1-month history of cough, exertional dyspnea, and fever. Two years earlier, he had been diagnosed with colorectal cancer and treated with resection and adjuvant chemotherapy (fluorouracil and folinic acid). Nine months before his current visit, he was diagnosed with metastatic disease in his lungs and pelvis and had completed eight cycles of combination chemotherapy (capecitabine, irinotecan, and bevacizumab every 3 weeks), resulting in a significant reduction in tumor burden. At the clinic visit, his scheduled ninth cycle of chemotherapy was postponed, and he was prescribed a 7-day course of empiric moxifloxacin for presumed bacterial pneumonia