The heart in acute leukemia. A study of 420 autopsy cases
Author:
Roberts WC, Bodey GP, Wertlake PT
Date: 2 July 2009
Abstract:
The heart of a patient with acute leukemia may function abnormally because of several factors : leukemic cell infiltrates or hemorrhages in its wall, hypoxia resulting from associated severe anemia, a cardiac or systemic infection, an underlying cardiac disease or a combination of these factors. Most previous studies of the heart in patients with acute leukemia have centered mainly on the incidence and extent of the cardiac leukemic cell infiltrates and on the clinical and electrocardiographic alterations resulting from them. Few reports have mentioned cardiac hemorrhages or the types and incidence of cardiac infections that are prevalent in patients with acute leukemia. The present study describes the cardiac findings in 420 patients with acute leukemia and attempts to correlate the pathologic observations
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