Author:

Cai Y, Cheng X, Zhan JH, Luo JH, Liao WW.

Date: 20 March 2023

Abstract:

Invasive fungal infection (IFI) is one of the serious complications in burn patients. The gradual development and application of broad-spectrum antibiotics in recent years has led to a serious dysbiosis of the flora, while the widespread prophylactic use of antifungal drugs has led to an increasing number of drug-resistant fungi. The clinical treatment of IFI is difficult and the prognosis is poor. The mortality of burn patients caused by IFI is increasing year by year. This paper reviews the epidemiologic characteristics, related risk factors, diagnostic methods, and treatment progress of IFI after burns, aiming to provide new ideas and reference for the prevention and treatment of IFI after burns.

[侵袭性真菌感染（IFI）是烧伤患者严重的并发症之一。近年来广谱抗生素的逐步研发应用致使菌群严重失调，而抗真菌药物的广泛预防性使用则导致耐药真菌日渐增加。IFI临床治疗难度大，预后差，IFI所致烧伤患者的病死率逐年上升。该文从烧伤后IFI的流行病学特点、相关危险因素、诊断方法及治疗进展方面进行综述，旨在为烧伤后IFI的预防和治疗提供新的思路及依据。.]

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